About this trial
Investigating the Impact of Combined Inhaled Nitric Oxide and Prone Positioning on the Efficacy in ARDS Patients
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age 18-80 years;
Patients with moderate to severe ARDS on mechanical ventilation
Disqualifiers
Patients with severe asthma or acute exacerbation of chronic obstructive pulmonary disease (COPD), lung tumors, post-lung resection, and post-lung transplantation.
Patients with hemodynamic instability requiring vasopressor support: dopamine or dobutamine >15 µg/kg/min, norepinephrine >0.3 µg/kg/min.
Cardiogenic pulmonary edema.
Patients with severe facial deformities, facial trauma, or severe thoracoabdominal trauma that precludes prone positioning ventilation.
Trial design
Single group
Treatments tested in this trial
inhaled nitric oxide combined with prone position ventilation
Procedure/Surgeryinhaled nitric oxide combined with prone position ventilation
Treatment groups
Trial outcomes
Primary outcomes
Intratidal gas distribution
Sponsors and contacts
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