The purpose of this study is to examine the natural history and risk factors of osteoarthritis (OA) and to explore the relationship between metabolic factors and OA progression.
Aged 50 years and above
Long-term resident of the study area
Willing to participate and provide informed consent
Hearing, speech, or mental impairments preventing effective communication
Unable to complete scheduled follow-up visits
Pregnant or planning pregnancy during the study period
Any other condition deemed unsuitable for participation by the researchers
This study will include adults aged 50 years and above to investigate osteoarthritis risk factors and progression in a general population-based cohort.
Cohort
Prospective
Not listed
Incidence of Osteoarthritis
The occurrence of clinically diagnosed osteoarthritis based on imaging and clinical symptoms during the follow-up period.
Change in Joint Pain Severity (WOMAC Pain Subscale)
Evaluated using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain subscale (range: 0-20). Higher scores indicate worse pain.
Change in Physical Function (WOMAC Subscale)
Assessed using the WOMAC physical function subscale (range: 0-68). Higher scores indicate worse physical function.
Change in Physical Function (SF-36 Physical Function Domain)
Assessed using the SF-36 physical function domain (range: 0-100). Higher scores indicate better physical function.
Timed Up and Go Test (TUGT)
Measured in seconds; a shorter time indicates better mobility.
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This trial is not recruiting at the moment. You can still explore other options:
