Acupoint Stimulation Improves Cognition Under Hypoxia

ConditionCognition
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
Age18-50
SponsorZhihong LU

About this trial

Cognitive impairment is common in people who suffer from hypoxia. Acupuncture and related techniques can be used to improve hypoxia and treat cognitive impairment. In this trial the effect of transcutaneous electrical acupoint stimulation on cognitive impairment in people under hypoxia will be investigated.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Male, age from 18 to 50 years

Disqualifiers

cardiopulmonary dysfunction;

History of severe respiratory, circulatory, digestive, blood, ear-nose-throat system diseases;

A history of fever or respiratory infection within the last two weeks;

Drinking alcohol or poor sleep within the last 24 hours

Trial design

Design model

Crossover

Treatments tested in this trial

  • transcutaneous electrical acupoint stimulation

    Other intervention

    Electrodes are placed at acupoints and connected to the stimulator. Electrical stimulation is given for 2 hours.

Treatment groups

50 Participants
are divided into 2 treatment groups
Group A: transcutaneous electrical acupoint stimulationExperimental treatment 1 intervention
Group B: ControlNo intervention 0 interventions

Trial outcomes

Primary outcomes

1

cognitive function measured by eye-tracking at 1 hour after hypoxia

Time frame
1 hour after hypoxia
2

cognitive function measured by eye-tracking at 2 hours after hypoxia

Time frame
2 hours after hypoxia

Secondary outcomes

1

mean arterial blood pressure

Time frame
starting from 10 minutes before hypoxia to 2 hours after hypoxia, every 5 minutes for 2 hours and 10 minutes
2

heart rate

Time frame
starting from 10 minutes before hypoxia to 2 hours after hypoxia, every 5 minutes for 2 hours and 10 minutes
3

saturation of pulse oximetry

Time frame
starting from 10 minutes before hypoxia to 2 hours after hypoxia, every 5 minutes for 2 hours and 10 minutes
4

Cerebral oxygen saturation

Time frame
starting from 10 minutes before hypoxia to 2 hours after hypoxia, every 5 minutes for 2 hours and 10 minutes

Other outcomes

Sponsors and contacts

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Zhihong LU

Lead sponsor

Air Force Military Medical University, China

Sponsor institution

This trial is not recruiting at the moment. You can still explore other options: