Acute Effect of Exergaming Based Sitting Tai Chi
ConditionHealthy
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorHong Kong Metropolitan University
About this trial
This study examines whether a single session of exergaming-based seated Tai Chi can acutely improve working memory, executive function, and prefrontal cortical efficiency in younger and older adults, compared with seated stretching. Using a within-subject crossover design, 40 participants aged 18-30 years and 60-75 years will complete both conditions in counterbalanced order on separate days. Cognitive performance will be assessed with Flanker and n-back tasks, while prefrontal activity will be recorded with fNIRS over the dorsolateral, ventrolateral, and frontopolar prefrontal cortex. Neural efficiency will be estimated by integrating task performance with task-evoked oxygenated hemoglobin responses.
The Tai Chi intervention is a 40-minute seated, exergame-guided 12-form routine preceded and followed by brief warm-up and cool-down periods. The control condition is a time-matched seated stretching programme without Tai Chi-specific movements or game feedback. Both conditions will be delivered at light-to-moderate intensity and supervised for safety and adherence.
The study tests whether acute exergaming-based seated Tai Chi produces greater post-intervention improvements in cognitive performance and more efficient prefrontal activation than stretching, and whether these effects differ by age group. Findings may clarify how a feasible seated mind-body exergame influences acute cognitive and neural responses across the adult lifespan.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Are aged 18-30 years (young adult group) or 60-75 years (older adults)
Have no current regular participation (e.g., ≥1 session/week) in Tai Chi, martial arts, or other mind-body exercise (e.g., yoga or qigong) in the last 3-6 months
Have no self-reported or clinically documented history of mild cognitive impairment, dementia, or other neurological (e.g., stroke) or psychiatric disorders (e.g., schizophrenia) known to affect cognition
Score within the normal range on the Hong Kong version of Montreal Cognitive Assessment (HK-MoCA) based on established age- and education-adjusted cutoffs
Disqualifiers
Have medical conditions that may interfere with safe participation, including pacemaker implantation or prosthetic devices
Have serious orthopedic or cardiovascular disorders that could affect participation in exergaming training
Have significant motor or balance impairment that would prevent performing basic seated arm and trunk movements
Are currently undergoing other clinical trials or structured exercise or cognitive training programmes >2 times/week during the preceding three months
Trial design
Design model
Crossover
Treatments tested in this trial
Exergaming based sitting Tai Chi
BehavioralAn acute exergaming-based seated Tai Chi protocol will be adapted from a newly developed 12-week training programme by our team, and will be further aligned with acute Tai Chi session parameters reported by a previous Tai Chi study, including comparable total duration, work-rest structure, and target light-to-moderate intensity. Participants will perform upper-limb and trunk movements derived from traditional Tai Chi forms, adapted for a seated posture and integrated into an interactive exergame environment that provides visual feedback and performance scoring to enhance engagement and standardize practice. Movements will be paced using on-screen cues and visual and auditory signals to control tempo across participants.
Seated Stretching
BehavioralIn the seated stretching condition, participants will complete a series of structured, low-intensity exercise program that would contain comparable social interaction and enjoyment without providing any strength and balance training benefits of Tai Chi. This will match in overall duration and approximate movement amplitude to the Tai Chi sequence but without game-based feedback or Tai Chi-specific components.
Treatment groups
40 Participants
are divided into 2 treatment groupsGroup A: Seated stretchingActive comparator 1 intervention
Group B: Exergaming based sitting Tai ChiExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Prefrontal cortical activation during inhibitory control (Flanker task)
Prefrontal cortical activity (oxyhemoglobin concentration, µM) will be recorded using functional near-infrared spectroscopy (fNIRS) during the Eriksen Flanker Task, which assesses inhibitory control. Regions of interest include the dorsolateral prefrontal cortex (DLPFC), ventrolateral prefrontal cortex (VLPFC), and frontopolar prefrontal cortex (FPC). Measurements will be taken before and immediately after a single session of exergaming-based seated Tai Chi and a single session of seated stretching in a crossover design. Data will be reported separately for each condition. Unit of Measure: µM (micromolar) oxyhemoglobin concentration.
Time frame
Baseline (pre-session) and immediately post-session on 2 consecutive days (Day 1 and 2).2
Prefrontal cortical activation during working memory (n-back task)
Prefrontal cortical activity (oxyhemoglobin concentration, µM) will be recorded using functional near-infrared spectroscopy (fNIRS) during the n-back Task, which assesses working memory. Regions of interest include the dorsolateral prefrontal cortex (DLPFC), ventrolateral prefrontal cortex (VLPFC), and frontopolar prefrontal cortex (FPC). Measurements will be taken before and immediately after a single session of exergaming-based seated Tai Chi and a single session of seated stretching in a crossover design. Data will be reported separately for each condition. Unit of Measure: µM (micromolar) oxyhemoglobin concentration.
Time frame
Baseline (pre-session) and immediately post-session on 2 consecutive days (Day 1 and Day 2)Secondary outcomes
1
Inhibitory Control Performance on the Eriksen Flanker Task - reaction time
Inhibitory control will be assessed using the computerized Eriksen Flanker Task. Participants will respond to the direction of a central target arrow flanked by congruent or incongruent distractor arrows. Reaction time (milliseconds) will be recorded for incongruent and congruent trials. The outcome metric is the difference in mean reaction time between incongruent and congruent trials (Flanker cost in milliseconds). Lower or less positive values indicate better inhibitory control. Unit of Measure: milliseconds
Time frame
Baseline (Pre-Session) and Immediately Post-Session on 2 consecutive days (Day 1 and Day 2)2
Working Memory Performance on the n-back Task - reaction time
Working memory capacity will be assessed using the computerized n-back Task (e.g., 2-back). Participants will view a sequence of stimuli and indicate whether the current stimulus matches the one presented n positions earlier. Reaction time (milliseconds) will be recorded for each correct response. Lower values indicate better performance (faster responses). The primary metric is the mean reaction time across all trials.
Time frame
Baseline (Pre-Session) and Immediately Post-Session on 2 consecutive days (Day 1 and Day 2).3
Title: Working Memory Performance on the n-back Task - Accuracy
Working memory capacity will be assessed using a computerized n-back task (e.g., 2-back). Participants will view a sequence of stimuli and indicate whether the current stimulus matches the one presented n positions earlier. Accuracy (percentage of correct responses) will be calculated. Higher values indicate better performance (fewer errors). The primary metric is the mean accuracy across all trials.
Time frame
Baseline (Pre-Session) and immediately post-session on 2 consecutive days (Day 1 and Day 2).4
Inhibitory Control Performance on the Eriksen Flanker Task - Accuracy
Inhibitory control will be assessed using the computerized Eriksen Flanker Task. Participants will respond to the direction of a central target arrow flanked by congruent or incongruent distractor arrows. Accuracy (percentage of correct responses) will be calculated for incongruent and congruent trials. The outcome metric is the difference in accuracy between incongruent and congruent trials (Flanker cost in percentage points). Higher or less negative values indicate better inhibitory control. Unit of Measure: percentage points
Time frame
Baseline (Pre-Session) and immediately post-session on 2 consecutive days (Day 1 and Day 2)Sponsors and contacts
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Source ClinicalTrials.gov