About this trial
The way people process and remember information may be related to adverse childhood experiences and Opioid Use Disorder symptoms. The purpose of this project is to examine brain function and performance during learning and memory tasks in adults. The study will compare measures of learning and memory across three groups of participants: those with an Opioid Use Disorder (OUD) that take buprenorphine for opioid replacement therapy, adults without an Opioid Use Disorder taking buprenorphine, and healthy adults that do not have an Opioid Use Disorder and are not taking buprenorphine.
Eligibility criteria
Qualifiers
Fluent in English
Able to give informed consent
Normal/corrected-to-normal vision and hearing
Diagnosis of OUD
Disqualifiers
Pregnancy
Significant medical or neurologic conditions (e.g., stroke, seizures, multiple sclerosis)
Actively suicidal
Contraindication for MRI
Trial design
Treatments tested in this trial
- Magnetic Resonance Imaging (MRI)
- Computer Tasks
Treatment groups
Sponsors and collaborators
University of Michigan
Lead sponsor
National Institute on Drug Abuse (NIDA)
Collaborator