Alveolar Ridge Preservation Using Autogenous Whole Tooth Graft With 1 %Metformin :A Randomized Controlled Clinical Trial

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorCairo University

About this trial

This study describes a technique used to preserve the bone dimensions after the tooth extraction inorder to facilitate later on the dental implant placement

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

18 years or older

patients requiring single extraction of non-molar tooth

extraction sockets having more than 50% buccal alveolar bone loss

Disqualifiers

Pregnancy

smokers

patients not maintaing good oral hygiene

presernce of acute endodontic infection in the tooth to be ectracted

Trial design

Design model

Parallel

Treatments tested in this trial

  • TEST 1

    Procedure/Surgery

    Autogenous whole tooth graft with metformin

  • Control

    Procedure/Surgery

    Autogenous whole tooth graft

Treatment groups

24 Participants
are divided into 2 treatment groups
Group A: TestExperimental treatment 1 intervention
Group B: ControlActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Radiographic buccolingual width ridge loss

Measuring the CBCT these dimensions pre operative and after 6 months

Time frame
6 months

Secondary outcomes

1

Alveolar buccal ridge height, lingual ridge height

Measuring them on CBCT pre operative and after 6 months

Time frame
6 months
2

the area percentage of newly formed bone, soft tissue and residual graft

By Histology after taking a biopsy after 6 months

Time frame
6 months
3

Patient satisfaction evaluation

by visual analog scale (0-10)

Time frame
2 weeks
4

Total number of analgesics taken in the first week

by asking the patient

Time frame
1 week

Other outcomes

Sponsors and contacts

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This trial is not recruiting at the moment. You can still explore other options: