About this trial
This study aims to compare the analgesic efficacy of multiple mid-transverse process to pleura (MTP) block and PCA in idiopathic scoliosis patients undergoing posterior spinal fusion surgery.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age ≥ 18 years.
Both sexes.
American Society of Anesthesiology (ASA) physical status I-II.
Idiopathic scoliosis patients undergoing posterior spinal fusion surgery.
Disqualifiers
Patients with pre-existing infection at block site.
Known allergy to study drugs.
Coagulation disorder.
History of psychiatric illness.
Trial design
Parallel
Treatments tested in this trial
Multiple Mid-Transverse Process to Pleura (MTP) Block
Other interventionPatients will receive multiple mid-transverse process to pleura (MTP) block after induction of anesthesia.
Morphine
DrugPatients will receive IV-PCA. Morphine is generally administered as an initial loading dose of 0.05-0.1 mg/kg before the end of surgery, with PCA settings of a bolus dose of 0.01-0.03 mg/kg, a lockout interval of 6-10 min, and a background infusion of 0.01-0.02 mg/kg/h.
Treatment groups
Trial outcomes
Primary outcomes
Degree of pain
The degree of pain will be assessed using the Visual Analogue Scale (VAS). VAS (0 represents "no pain" while 10 represents "the worst pain imaginable"). VAS will be assessed at 0, 4, 8, 12, 18 and 24h postoperatively.
Secondary outcomes
Intraoperative fentanyl consumption
Additional fentanyl bolus dosages of 1 µg/kg IV will be administered if heart rate or mean arterial blood pressure elevated more than 20% of the baseline (after exclusion of other causes than pain).
Time to the first request for the rescue analgesia
Time to the first request for the rescue analgesia (time from end of surgery to first dose of morphine administrated).
Total morphine consumption
Postoperative analgesia was provided by morphine (3 mg IV in Multiple Mid-Transverse Process to Pleura (MTP) Block group or 0.01 mg/kg bolus with a 15-min lockout in PCA group) to keep the Visual Analogue Scale (VAS) at rest less than 4.
Mean arterial pressure
Mean arterial pressure will be recorded preoperatively, before the block is performed, and every 15 minutes until the end of the surgery.
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