This study looks at how different antibiotic treatments affect patients in intensive care who have pneumonia caused by the bacteria Stenotrophomonas maltophilia. It compares using one antibiotic versus two antibiotics, and treatment lengths of 7 days versus 14 days, to see which approach helps patients survive better. The study also examines how resistant the bacteria are to antibiotics and how often the pneumonia comes back.
Adult patients (age ≥ 18 years)
Hospitalized in Medical Intensive Care Unit between January 1, 2018, and December 31, 2023
Intubated and mechanically ventilated
Diagnosed with ventilator-associated pneumonia caused by Stenotrophomonas maltophilia
Patients under 18 years old
Patients who refuse the use of their data for research purposes
The study population consists of adult patients admitted to the Medical Intensive Care Unit (ICU) between January 2018 and December 2023 who are intubated and mechanically ventilated, and who develop ventilator-associated pneumonia caused by Stenotrophomonas maltophilia. These patients represent a critical care group at high risk for serious infections with multidrug-resistant bacteria.
Cohort
Retrospective
Not listed
patient survival based on the antibiotic treatment strategy used (monotherapy vs. combination therapy and 7 vs. 14 days duration).
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