Assessing the Role of Proton Pump Inhibitors in Reducing Aspiration Incidence in Pediatric Laryngomalacia Cases

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age6-5
SponsorMinia University

About this trial

Laryngomalacia is the most common congenital laryngeal anomaly in children and is frequently associated with aspiration. This randomized controlled study aims to assess the role of proton pump inhibitor (PPI) therapy in reducing the incidence of aspiration in pediatric patients with laryngomalacia. Eligible participants will be randomly assigned to either a PPI treatment group or a control group. Clinical and swallowing assessments will be performed to compare aspiration incidence and swallowing outcomes between the two groups

Eligibility criteria

Qualifiers

Children diagnosed with laryngomalacia by laryngoscopic examination with a history of recurrent choking attacks or aspiration symptoms.

Children aged from 6 months to 5 years.

Disqualifiers

Children with any neurological impairment.

Children with other congenital anomalies.

Children with other causes of respiratory distress

Trial design

Treatments tested in this trial

  • PPI
  • vitamin D
  • feeding instruction

Treatment groups

60 Participants
are divided into 2 treatment groups

Sponsors and collaborators