About this trial
Laryngomalacia is the most common congenital laryngeal anomaly in children and is frequently associated with aspiration. This randomized controlled study aims to assess the role of proton pump inhibitor (PPI) therapy in reducing the incidence of aspiration in pediatric patients with laryngomalacia. Eligible participants will be randomly assigned to either a PPI treatment group or a control group. Clinical and swallowing assessments will be performed to compare aspiration incidence and swallowing outcomes between the two groups
Eligibility criteria
Qualifiers
Children diagnosed with laryngomalacia by laryngoscopic examination with a history of recurrent choking attacks or aspiration symptoms.
Children aged from 6 months to 5 years.
Disqualifiers
Children with any neurological impairment.
Children with other congenital anomalies.
Children with other causes of respiratory distress
Trial design
Treatments tested in this trial
- PPI
- vitamin D
- feeding instruction