Assessment of Hard and Soft Tissue Changes Following XCM Versus FGG Simultaneous With Delayed Dental Implant Placement

ConditionMissing Teeth
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-55
SponsorCairo University

About this trial

Teeth loss are usually associated with alterations of extraction sockets result in obviously absorbed alveolar ridges and are often accompanied with soft tissue atrophy such as narrow keratinized tissue and a shallow vestibule.

Lack of peri-implant keratinized tissue is a potential risk to peri-implant diseases. Although the role of width of KM in maintaining peri-implant health is a controversial topic, the majority of high-level evidence has suggested that a minimum KM width (KMW) of 2 mm around the dental implants is critical to maintain peri-implant health and the long-term survival of dental implants.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Adults above the age of 18 years.

Presence of 2mm or less of keratinized tissue width

Sufficient alveolar ridge width minimum of 6 mm

Patients with good oral hygiene as evidenced by plaque index (PI)<1 and showing cooperation or compliance with treatment.

Disqualifiers

Patients diagnosed with periodontal diseases (Caton et al., 2018).

Acute active infection at implant sites

Patients with medical conditions that would compromise the surgical procedures; uncontrolled diabetes mellitus, taking intravenous bisphosphonates for treatment of osteoporosis and radiotherapy

Patients with parafunctional habits.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Free gingival graft simultaneous with delayed implant placement

    Procedure/Surgery

    XCM grafts (of bovine origin)

  • Xenogeneic collagen matrix simultaneous with delayed implant placement

    Procedure/Surgery

    A FGG will be harvested from the palate between first premolar and first molar

Treatment groups

24 Participants
are divided into 2 treatment groups
Group A: Xenogeneic collagen matrix simultaneous with delayed implant placementExperimental treatment 1 intervention
Group B: Free gingival graft simultaneous with delayed implant placementActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Keratinized tissue width

mm

Time frame
One year
2

graft shrinkage

precentage

Time frame
One year
3

marginal bone loss

mm

Time frame
One year

Secondary outcomes

Other outcomes

Sponsors and contacts

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Cairo University

Lead sponsor

MTI University

Sponsor institution

MTI University

Collaborator

This trial is not recruiting at the moment. You can still explore other options: