Assessment of Hematologic Indices in Juvenile Lupus Erythematosus Patients:Correlation With Disease Activity and Chronic Organ Damage in These Patients

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeUp to 18
SponsorSohag University

About this trial

The study aim to evaluate the relationship between some important hematologic indices in juvenile lupus erythematosus patients and if these indices may be use as markers of disease acitivity in these patients or not ,also evaluate the relationship with these markers and chronic organ damage index

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

patients who fillful 2012 SLICC criteria or 2019 ACR/EULAR criteria of systemic lupus erythematosus

Age of patients at disease onset before 18 years

Disqualifiers

Adult onset disease ( age at disease onset after 18 years

Any other chronic inflamatory disorders or other autoimmune diseases

Trial population

Patients males or females below age of 18 years diagnosed as juvenile systemic lupus erythematosus based on 2012 SLICC criteria or 2019 ACR/EULAR criteria

Trial design

Design model

Case-control

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

Calculation of hematological indices in juvenile lupus erythematosus patients

Calculation of systemic inflamatory index,systemic information response index and aggregate index of systemic inflamation ,and correlate these indices to SLE disease activity index

Time frame
3_ 6 months
2

Correlation between hematologic indices in juvenile lupus erythematosus patients and disease activity in these patients

SLEDAI score in juvenile lupus erythematosus patients

Time frame
3-6 months

Secondary outcomes

1

Calculation of chronic damage index in juvenile lupus erythematosus patients

SLICC/ACR score in juvenile lupus erythematosus patients

Time frame
3_6 months
2

Relationship between hematologic index and chronic organ damage index in juvenile lupus erythematosus patients

SLICC/ACR score

Time frame
3-6 months

Other outcomes

Sponsors and contacts

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