Assessment of Peridontal Inflamatuar Markers in MIH
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age8-13
SponsorMarmara University
About this trial
The goal of this observational study is to investigate periodontal inflammatory mediators in systemically healthy children aged 8-13 years with and without molar-incisor hypomineralization (MIH) who require initial periodontal treatment due to gingivitis.
The main questions it aims to answer are:
Are the levels of periodontal inflammatory mediators in gingival crevicular fluid different between children with MIH and those without MIH? Is the presence and severity of MIH associated with clinical periodontal parameters and dentin hypersensitivity?
Researchers will compare children with MIH to children without MIH to determine whether MIH is associated with changes in periodontal inflammatory mediator levels and periodontal clinical findings.
Eligibility criteria
Qualifiers
Systemically healthy children aged 8-13 years (both sexes).
Children who demonstrate adequate cooperation for dental treatment and study procedures (Frankl Behavior Rating Scale score ≥3).
Study group: Children with molar-incisor hypomineralization (MIH) affecting at least three permanent first molars and requiring initial periodontal treatment for gingivitis.
Control group: Children without molar-incisor hypomineralization who require initial periodontal treatment for gingivitis.
Disqualifiers
Use of antibiotics within the previous 1 month.
Radiographic evidence of periodontal destruction.
History of periodontal treatment within the previous 3 months.
Presence of systemic, chronic, or metabolic diseases.
Trial design
Treatments tested in this trial
- Initial periodontal treatment
Treatment groups
76 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov