This prospective observational study aims to investigate the association between maternal thyroid function, maternal anxiety levels, and fetal cardiotocography parameters in high-risk pregnancies. Pregnant women at 32 weeks of gestation or later who are followed in the perinatology outpatient clinic for high-risk pregnancy will be included.
Maternal thyroid function test results, including thyroid-stimulating hormone (TSH) and free thyroxine (fT4), obtained as part of routine clinical care will be recorded. Maternal anxiety will be assessed using the Beck Anxiety Inventory. Fetal well-being will be evaluated using a routine 20-minute non-stress test (NST), including baseline fetal heart rate, accelerations, reactivity, and the presence of decelerations.
The associations between maternal anxiety scores, thyroid hormone levels and thyroid status, and fetal cardiotocography parameters will be analyzed. Sociodemographic and obstetric characteristics will also be evaluated in relation to these parameters.
Singleton pregnancy at 32 weeks of gestation or later
Pregnancy being followed as a high-risk pregnancy
Age between 18 and 45 years
Availability of routine thyroid function test results and non-stress test assessment
Gestational age below 32 weeks
Multiple pregnancy
Fetal conditions that may affect interpretation of the non-stress test tracing
Acute maternal infection
The study population will consist of women with high-risk singleton pregnancies at 32 weeks of gestation or later who are followed at the Perinatology Outpatient Clinic of Istanbul Training and Research Hospital and who undergo routine thyroid function testing and non-stress testing.
Cohort
Prospective
Not listed
Association Between Maternal Anxiety Level and NST Parameters
The association between Beck Anxiety Inventory scores and fetal non-stress test parameters will be evaluated.
Association Between Maternal Thyroid Function and NST Parameters
The association between maternal TSH and free T4 levels and fetal non-stress test parameters will be evaluated.
Association of Sociodemographic and Obstetric Characteristics With Maternal Anxiety, Thyroid Function, and NST Parameters
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