The goal of this clinical trial is to evaluate the effect of a long-term, individualized, hybrid adapted physical activity program on the quality of life of patients with multiple myeloma. The main question it aims to answer are :
Does this logn term, individualized and hybrid adapted physical activity program improve quality of life in multiple myeloma patient ? What are the effects of this program on effort tolerance, pain, muscular mass, osteolytic lesions, tolerance to treatment, response to treatment? If there is a comparison group: Researchers will compare \[arm information\] to see if \[insert effects\].
Participants will be randomised in 2 groups.
* control group: patients will receive only advices about physical activities benefit * interventional group: This group will be offered a program of adapted physical activities mixing sessions at home (remote) and sessions at the hospital (in person).
newly diagnosed or relapse multiple myeloma, > 60 yo, not eligible to transplant
1st to 4th line of treatment initiated during the last 3 months
receiving a systemic treatment that involved visit to the hospital at least twice a month durig the first 3 months and at least once a month the next 3 months
severe cardiac amyloidosis
absolute contraindication to physical activity
inability to comply with the protocol requirements
not french speaker
Parallel
Adapted physical activity
Procedure/Surgerythe intervention is a "real life"6 months adapted physical activity program which is individualised and hybrid (presential and distancial) . It includes a session in presential (at hospital) every 2 weeks for the first 3 months then once a month and 3 sessions par week for 6 months at home.
compare EORTC-QLQ-C30 summary score at 6 months between both groups
EORTC-QLQ-C30 questionnaire will be given to participant at inclusion and at 6 months, score will be calculated
compare functional and symptomatic dimension of EORTC-QLQ-C30 at 3 and 6 months between both groups
score of functional and symptomatic dimension of EORTC-QLQ-C30 will be calculated and compared between both groups
study the effect of 6 months intervention on objective and subjective level of physical activity
mean daily time in moderate to elevate intensity during intervention and IPAQ score at 3 and 6 months
study effect of 6 months of intervention on bone pain (FACT-Bone) evolution
compare FACT-Bone pain score at 3 and 6 months betaween both groups
Study effect of 6 months intervention on muscular mass
compare between both groups muscular surface on CT scan at L3 level at 6 months
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