Bilateral Erector Spinae Plane Block Versus Bilateral Oblique Subcostal Transversus Abdominis Plane Block for Postoperative Analgesia in Colorectal Surgery

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorCairo University

About this trial

This study aims to compare the ultrasound-guided bilateral erector spinae plane block (ESPB) and oblique subcostal transverse abdominal plane block (OSTAPB) for postoperative analgesia in colorectal surgery.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age 18 to 75 years old.

Both sexes.

American Society of Anesthesiologists (ASA) physical status II-III.

Scheduled for open colorectal surgery under general anesthesia.

Disqualifiers

History of opioid abuse.

Chronic opioid consumption.

Body mass index (BMI) ≥ 35 kg/m2.

Severe cardiac insufficiency, defined as New York Heart Association (NYHA) class III or IV heart failure.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Erector Spinae Plane Block

    Other intervention

    Patients will receive ultrasound-guided erector spinae plane block.

  • Oblique Subcostal Transversus Abdominis Plane Block

    Other intervention

    Patients will receive ultrasound-guided oblique subcostal transversus abdominis plane block.

Treatment groups

50 Participants
are divided into 2 treatment groups
Group A: Group IExperimental treatment 1 intervention
Group B: Group IIExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Degree of pain

Each patient will be instructed about postoperative pain assessment with the numeric rating scale (NRS). NRS (0 represents "no pain" while 10 represents "the worst pain imaginable"). NRS will be assessed at 0, 2, 4, 6, 12, and 24 h postoperatively.

Time frame
24 hours postoperatively

Secondary outcomes

1

Time to the first rescue analgesia

Time to the first request for the rescue analgesia will be recorded from end of surgery to first dose of morphine administrated.

Time frame
24 hours postoperatively
2

Intraoperative fentanyl consumption

Additional fentanyl bolus dosages of 1 µg/kg IV will be administered if heart rate or mean arterial blood pressure elevated more than 20% of the baseline (after exclusion of other causes than pain).

Time frame
Intraoperatively
3

Total morphine consumption

Rescue analgesia of morphine will be given as 3 mg bolus (maximum dose of 0.5 mg/kg/24hours) if the numeric rating scale (NRS) \> 3 to be repeated after 30 min if pain persists until the NRS \< 4.

Time frame
24 hours postoperatively
4

Mean arterial pressure

Mean arterial pressure will be recorded at: * T0: Baseline reading preoperatively (in the preoperative holding area). * T1: Immediately before intubation. * T2: 15 minutes after intubation. * T3: 30 minutes after intubation. * T4: 45 minutes after intubation. * T5: 60 minutes after intubation. * T6: At the end of surgery.

Time frame
Till end of surgery (Up to 2 hours)

Other outcomes

Sponsors and contacts

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