The CMUBCS is a birth cohort study located in Shenyang, China. Its initial aim is to facilitate research on understanding the interplay between genes and environmental factors on disease etiology. Data are collected regarding environmental factors, family and lifestyle, clinical experimental outcomes and imaging results of pregnant women and children from birth to 18 years old. Biological samples including blood and tissue samples are also collected from the children and their parents.
Pregnant women, <13 gestational weeks
Permanent residents or families intended to remain in Shenyang and surrounding areas
Pregnant women who are planned to be examined and delivered in Shengjing Hospital.
Pregnant women who refuse to take part in the study
Pregnant women have diseases that might affect the results of researches, including neuropsychiatric disorders.
Pregnant women in Shenyang, China and their husband and children
Cohort
Prospective
Not listed
Change of biometric parameter in centimeter of fetuses at the thirteenth week of gestational age
Including head circumference, abdominal circumference, biparietal diameter, femur length of singleton and twin pregnancy
Weight in kilogram of neonate
Including singleton and twin pregnancy measured by nurses
Gene expression of husbands of pregnancy women
DNA methylation, histone acetylation etc. assessed by analyses of blood
Change of gene expression of pregnancy women
DNA methylation, histone acetylation etc. assessed by analyses of blood
Change of intestinal flora during early childhood
Assessed by analyses of stool samples
Height in centimeter changes during childhood
Measured by nurses in clinic
Weight in kilogram changes during childhood
Measured by nurses in clinic
Change of gene expression during childhood
DNA methylation, histone acetylation etc. assessed by analyses of blood
Click on the lead sponsor to view all of their trials.
