Building Cognitive Resilience to Vaccine Misinformation Using AI in Europe
ConditionHealthy
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age20+
SponsorLondon School of Hygiene and Tropical Medicine
About this trial
This multi-country trial evaluates an AI chatbot designed to counter cognitive biases and inoculate parents against vaccine misinformation, embedded within a large survey across five European countries (n=5,000). Scaled from a 2026 single-country study, outcomes compare behavioural and attitudinal responses against standard-of-care materials (e.g., UNICEF infographics) to identify effective, scalable misinformation interventions.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Parents or caregivers with children under 18 years old in the five target countries (UK, Netherlands, Croatia, Latvia, and Slovakia); and
Those who have regular access to a digital device and the internet
Disqualifiers
Participants who do not meet the inclusion criteria.
Trial design
Design model
Parallel
Treatments tested in this trial
AI-driven chatbot
BehavioralA tailored AI-driven chatbot designed to counter vaccine misinformation.
Social media infographic
BehavioralA UNICEF social media infographic with three "myth vs. fact" statements on vaccination.
Treatment groups
5,000 Participants
are divided into 2 treatment groupsGroup A: AI-driven chatbotExperimental treatment 1 intervention
Group B: Social media infographicActive comparator 1 intervention
Trial outcomes
Primary outcomes
1
Parental susceptibility to misinformation about childhood vaccination
The primary outcome of this study will assess parental susceptibility to misinformation about childhood vaccination, defined as parents' ability to accurately distinguish between true and false vaccine-related information. This will be measured using ten statements on childhood vaccines, including four true and six false, rumour-related statements. Two of the rumour-related statements correspond to each of the three misinformation tactics introduced by the chatbot and the UNICEF infographic. This measure reflects parents' ability to identify misinformation containing manipulation tactics they were inoculated against and to distinguish true from false information regarding childhood vaccination. Responses will be recorded as "True", "False", or "Don't know". A composite misinformation susceptibility score will be calculated based on the number of correct responses, with higher scores indicating greater ability to identify vaccine misinformation accurately.
Time frame
Through study completion, an average of 20-30 minutesSecondary outcomes
1
Vaccine confidence
Vaccine confidence will be assessed using three statements addressing whether childhood vaccines are important, safe, and effective. Responses will range from "Strongly agree" to "Strongly disagree", with a "Don't know" option. A composite score ranging from 0 to 100 will be calculated, with higher scores indicating greater vaccine confidence.
Time frame
Through study completion, an average of 20-30 minutesSponsors and contacts
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Source ClinicalTrials.gov