About this trial
This prospective observational analytical study aims to assess the diagnostic value of Cancer Ratio and Cancer Ratio Plus in differentiating malignant pleural effusion from tuberculous pleural effusion. Adult patients with confirmed malignant or tuberculous pleural effusion will be recruited from the Chest Diseases Department, Sohag University Hospitals. Clinical, laboratory, and radiological data will be collected, and the diagnostic performance of both markers will be evaluated.
Eligibility criteria
Qualifiers
Adult patients (≥18 years)
Patients with Malignant or tuberculous pleural effusion
Availability of complete pleural fluid analysis including lymphocyte percentage ,pleural fluid ADA, and Serum LDH level
Disqualifiers
Patients with mixed etiology effusions (e.g., malignancy with infection)
Prior pleural interventions affecting fluid analysis
Incomplete clinical or laboratory data
Trial design
Treatments tested in this trial
- Cancer Ratio and Cancer Ratio Plus