About this trial
nephrotic syndrome (NS) is one of the most common pediatric kidney diseases There is an increased incidence of heart disease in patients with primary nephrotic syndrome (PNS) compared to the normal population Conventional Echocardiography is usually utilized to diagnose myocardial dysfunction. Tissue Doppler imaging is a non-invasive cardiac imaging technique which measures the velocity of the longitudinal motion of the mitral annulus, tricuspid annulus and the basal part of interventricular septum
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Children with primary nephrotic syndrome.
Age: 2 - 14 years.
Both males and females
Disqualifiers
Patients of primary cardiac diseases (e.g., congenital or rheumatic heart disease, cardio- myopathy).
Trial design
Parallel
Treatments tested in this trial
Tissue Doppler imaging and Conventional Echocardiography
Devicenon-invasive cardiac imaging technique which measures the velocity of the longitudinal motion of the mitral annulus, tricuspid annulus and the basal part of interventricular septum
Treatment groups
Trial outcomes
Primary outcomes
cardiac performance evaluation in children with steroid dependent vs steroid resistant nephrotic syndrome
compairing of myocardial performance index (MPI)(Tei index) in nephrotic dependant and resistant nephrotic syndrom by calculating ejection time (ET) of right and left ventricle and mitral closure time (MCT) using tissue doppler
Sponsors and contacts
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