ChAracterization of Normal and Pathological moRphological Variations of the TEMporomandibular Joint by Real-time magnetIc reSonance Imaging

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorCentral Hospital, Nancy, France

About this trial

The Real Time MRI Rapid Flash sequence is particularly interesting for the study of moving organs and joints.

This sequence will make it possible to characterize normal and pathological temporomandibular joint movements by MRI.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Adult: age ≥ 18 years old;

Person with the capacity to understand the instructions given;

Person affiliated to a social security scheme or beneficiary of such a scheme;

Person having received complete information on the organization of the Clinical Investigation and having signed informed consent.

Disqualifiers

Person with large-scale metallic dental reconstructions;

Edentulism more than 5 teeth;

Claustrophobia;

Contraindication to performing an MRI examination

Trial design

Design model

Parallel

Treatments tested in this trial

  • MRI with Real Time MRI Rapid Flash sequence

    Device

    MRI examination of temporomandibular joint with Real Time MRI Rapid Flash sequence

Treatment groups

60 Participants
are divided into 2 treatment groups
Group A: HealthyOther 1 intervention
Group B: Temporomandibular Joint DisordersOther 1 intervention

Trial outcomes

Primary outcomes

1

Curve representing the difference between displacement of condyles during Temporo Mandibular Joint (TMJ) movements in healthy subjects and in subjects with known Temporo Mandibular Disorder (TMD).

Time frame
Baseline (day 0)

Secondary outcomes

1

Curve representing the displacement of the articular discs during TMJ movements

Time frame
Baseline (day 0)
2

Curve representing the difference between displacement of joint discs during TMJ movements in healthy subjects and in subjects with known TMD

Time frame
Baseline (day 0)
3

Characterization of the volume in mm3 of the main masticatory muscles during movement by MRI in healthy and pathological subjects.

Time frame
Baseline (day 0)

Other outcomes

Sponsors and contacts

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