Children Acceptance of AgNP Mouthwash Against Chlorhexidine Mouthwash
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age6-12
SponsorCairo University
About this trial
This study aims to evaluate and compare the children's acceptance of mouthwash containing silver nanoparticles versus Chlorhexidine.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Children aged from 6 to 12 in good general health and medically free
Cooperative patient who will care about attending the follow-up visit
Acceptance of the parents to sign the informed consent
Composite restoration on anterior teeth
Disqualifiers
Children who are unable to attend the follow-up visit
Medically compromised patient
Handi-capped patient
Parents refuse to sign informed consent
Trial design
Design model
Parallel
Treatments tested in this trial
nano silver mouthwash
Other interventionnano silver mouthwash will reduce the side effect of chlorhexidine and increase acceptance of the mouthwash to patients
Chlorhexidine mouthwash (0.12%)
Other interventionthe concentration of chlorhexidine
Chlorhexidine mouthwash (0.2%)
Other interventionchlorhexidine mouthwash 0.2% (orovex )
Treatment groups
60 Participants
are divided into 3 treatment groupsGroup A: use AgNP mouthwash as experimental groupExperimental treatment 1 intervention
Group B: use hexitol mouthwash (CHX) as experimental groupExperimental treatment 1 intervention
Group C: orovex mouthwash (CHX) as a comparator groupActive comparator 1 intervention
Trial outcomes
Primary outcomes
1
children acceptance and compliance
it will be measured by likert scale (1-5) 1 (strongly disagree) 5 (strongly agree)
Time frame
15 daysSecondary outcomes
1
Gingival health
\* gingival inflammation measured by modified gingival index scoring criteria (0-4) 0 (Normal gingiva ) 4 (sever inflammation of gingiva)
Time frame
15 days2
plaque thickness at gingival margin
\* measure plaque thickness at gingival margin by plaque index by loe and silness scoring criteria (0-3) 0 (no plaque) 3 (thick plaque)
Time frame
15 days3
color stability of composite restoration of anterior teeth
measure color stability of composite restoration of anterior teeth ΔE\* = √((L₂ - L₁)² + (a₂ - a₁)² + (b₂ - b₁)² Where: L\* = Lightness (0 = black, 100 = white) 1. = Red-Green axis (positive = red, negative = green) 2. = Yellow-Blue axis (positive = yellow, negative = blue * L1, a1, b1 = before exposure * L2, a2, b2 = after exposure A higher ∆E means more discoloration.
Time frame
15 daysLocations
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: