Health TrialsbyHealthPanel

Chongqing Diabetes Registry Study

ConditionDiabetes Mellitus
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-75
SponsorChongqing Medical University

About this trial

To investigate the risk factors and biomarkers of the microvascular disease，macrovascular disease and neuropathy in patients with diabetes.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Diagnosis of diabetes mellitus（based on the 1999 WHO diagnostic cretirial）;

Age younger than 75 years old, gender is not limited;

Voluntary to sign on the informed consent.

Disqualifiers

pregnant or breast-feeding women;

Patients with chronic disease requiring long-term glucocorticoid therapy;

Patients with severe infection (except for diabetic foot) or immune dysfunction.

Trial population

The subjects who diagnosed of diabetes mellitus and signed on the informed consent will be enrolled in our study. We intend to enroll hospitalized patients or outpatient with diabetes mellitus from Chongqing Diabetes Centre,Chongqing,China.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

The number of patients whoes Diabetic Kidney disease (DKD) is worsen

Worsen DKD is defined as Urine Albumin Creatinine Ratio （UACR）\> 300 mg/g Cr（twice out of three measures）, or 24 hours urinary protein\> 300 mg / 24 h, or double serum creatinine level and at least 200μmol/l (2.26 mg/dl), or require renal replacement therapy, or death due to kidney disease.

Time frame
5 years

Secondary outcomes

1

The number of patients who develop DKD

Diabetic Kidney Disease is defined as UACR \> 30 mg/g Cr（twice out of three measures），or estimated Glomerular Filtration Rate（eGFR）\<60ml/min/1.73m2.

Time frame
5 years
2

The number of patients who develop Diabetic Retinopathy

New Diabetic Retinopathy

Time frame
5 years
3

The number of patients whoes DR is worsen

Worsen DKD is defined as any eye with original Diabetic Rretinopathy aggravated by at least one level, or progress to proliferation retinopathy, or appearance of macular degeneration, or at least one eye with blindness (refer to the WHO standards, the Snellen-chart vision drop to 6/60 or less), or to accept retinal photocoagulation treatment, or accept vitrectomy.

Time frame
5 years
4

The number of patients who develop Diabetic Neuropathy

Diabetic Peripheral Neuropathy is defined as Neuropathy Symptom Score/Neuropathy Disability Score（NSS/NDS） with at least two positive outcomes, or electromyography examination to identify nerve damage；Diabetic Autonomic Neuropathy is defined as tachycardia at rest (Heart Ratio\>100bpm) and postural hypotension (standing position leads systolic blood pressure reduction \>20mmHg).

Time frame
5 years

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Chongqing Medical University

Lead sponsor

Source ClinicalTrials.gov
Apply now