Circulatory Exercise After Total Knee Replacement
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorAssiut University
About this trial
Total knee replacement is commonly associated with early postoperative inflammation, edema, pain, and reduced mobility. This randomized controlled trial will evaluate whether adding a simple circulatory exercise program to standard postoperative rehabilitation reduces early limb edema and inflammatory response after unilateral primary total knee replacement. Participants will be randomized to standard rehabilitation alone or standard rehabilitation plus seated and supine knee-extension exercises with alternating ankle dorsiflexion. The primary endpoint is change in limb edema measured by standardized limb circumference at postoperative day 14.
Eligibility criteria
Qualifiers
Adults ≥ 18 years undergoing elective unilateral primary TKR for osteoarthritis.
Able to provide informed consent.
Able to perform the exercise (cognitively and physically) prior to discharge.
Disqualifiers
Preexisting peripheral vascular disease with severe ischemia or venous insufficiency that limits exercise.
Contraindication to early active movement per surgeon (e.g., complex surgical fixation limiting motion if present).
Severe neurological or cognitive impairment preventing instruction adherence.
Inability to comply with follow-up.
Trial design
Treatments tested in this trial
- standard postoperative TKR rehabilitation
- Standard Rehabilitation Plus Circulatory Exercise
Treatment groups
68 Participants
are divided into 2 treatment groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov