This study is a prospective, randomized controlled, single-blind, multicenter study design. To evaluate the safety and efficacy of traditional pulmonary vein isolation (PVI) alone and PVI combined with Bachmann bundle ablation on persistent atrial fibrillation.
According to the treatment strategy, they were divided into two groups. Control group: circumferential PVI alone group (CPVI). Experimental group: CPVI combined with Bachmann bundle ablation group (CPVI-BBM).
Subjects≥ 18 years old and ≤ 75 years old;
the subject was diagnosed with persistent atrial fibrillation (duration of ≥6 months and ≤ 3 years);
Able to understand the purpose of the trial, voluntarily participate in this study, the subject or his legal representative signed the informed consent form, and was willing to complete the follow-up according to the requirements of the protocol.
Previous atrial fibrillation catheter ablation therapy, left atrial appendage closure or atrial fibrillation surgery;
atrial fibrillation secondary to electrolyte imbalances, thyroid disease or other reversible disease, or non-cardiac causes;
Left atrial or left atrial appendage thrombus (confirmed by esophageal ultrasound or CT examination);
Patients with pulmonary vein stenosis or pulmonary vein stents implanted;
Parallel
Traditional pulmonary vein isolation (PVI) ablation
Procedure/SurgeryTraditional pulmonary vein isolation (PVI) ablation
Bachmann bundle modification
Procedure/SurgeryBachmann bundle modification
Sinus rhythm maintenance rate after ablation in the CPVI group and CPVI-BBM group at 1 year.
Immediate success rate of surgery
Direct termination rate of intraoperative atrial fibrillation
The number of cardioversions
Total operative time (defined as the total time from the first femoral venous puncture to the final catheter removal)
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This trial is not recruiting at the moment. You can still explore other options:
