Clinical and Radiographic Outcomes of Lesion Sterilization and Tissue Repair Using Zinc Oxide/ 6-gingerol Mix Versus Triple Antibiotic Paste in Non-vital Primary Molars

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age4-8
SponsorAl-Azhar University

About this trial

This study aims to evaluate and compare the clinical and radiographic outcomes of Lesion sterilization and tissue repair using zinc oxide/ 6-gingerol mix versus triple antibiotic paste in non-vital primary molars.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age from 4 to 8 years.

Both sexes

Children must have at least two restorable non-vital primary molars

Periapical radiolucency.

Disqualifiers

Presence of systemic diseases.

Teeth with physiological mobility near exfoliation time.

Teeth with vital pulp.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Zinc oxide/ 6-gingerol mix

    Other intervention

    Lesion sterilization and tissue repair (LSTR) using zinc oxide/ 6-gingerol mix.

  • Triple antibiotic paste

    Other intervention

    Lesion sterilization and tissue repair (LSTR) using triple antibiotic paste.

Treatment groups

60 Participants
are divided into 2 treatment groups
Group A: Group AExperimental treatment 1 intervention
Group B: Group BActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Assessment of pain

Pain will be assessed using age-appropriate pain scales (5-point Likert scale for children) with 0 typically representing "no pain" and 4 representing "very high/extreme pain".

Time frame
6 months postoperatively

Secondary outcomes

1

Tooth mobility

Tooth mobility is the horizontal or vertical looseness of a tooth beyond its normal physiological range. It is graded from 0 (no mobility) to 3 (severe, \>2mm or vertical movement).

Time frame
One year postoperatively

Other outcomes

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