About this trial
This study will evaluate the clinical and radiographic performance of resin composite restoration after utilized a grape seed extract as dentin biomodification in vital teeth with deep occlusal carious lesions (ICDAS 5-6) after selective soft dentin removal technique.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Adult patients (age: 22-42 years) of both genders.
Good oral hygiene.
Willing to sign the informed consent.
Co-operative patients who accept the follow-up period.
Disqualifiers
Allergy to any of the restorative materials.
Patients undergoing orthodontic treatment with fixed appliances.
Pregnant women.
Patients with debilitating systemic diseases.
Trial design
Parallel
Treatments tested in this trial
15% Grape seed extract as dentin pretreatment
Other interventionusing proanthocyanidin-rich grape seed extract as a biomodifier for dentin improved the mechanical properties of dental collagen by cross-linking and dehydrating fibrils. This made the collagen substrate more suitable for hybridization. It also acted as a non-specific MMP-inhibitor, protecting exposed collagen fibrils from biodegradation from dentin proteases.
Treatment groups
Trial outcomes
Primary outcomes
Clinical Performance (Biological properties), Revised FDI criteria. (Clinically excellent-Success rate)
Postoperative hypersensitivity and pulpal status/ Caries at restoration margins (CAR), Scores 1. clinically very good 2. clinically good 3. clinically sufficient 4. clinically unsatisfactory 5. clinically poor
Secondary outcomes
Radiographic Assessment, Digital radiography
Greyscale values ranged from 0 (black pixel) to 255 (white pixel).
Locations
Sponsors and contacts
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This trial is not recruiting at the moment. You can still explore other options: