RATIONALE: Collecting and storing samples of tissue from patients with cancer to test in the laboratory may help the study of cancer in the future.
PURPOSE: This research study is collecting tissue samples from patients with cancer undergoing radiation therapy. Healthy participants will also be allowed on the trial so their samples can be used in comparison to patients with malignancy
Pathologically-proven diagnosis of malignancy
Planning treatment with radiation therapy
Able to perform follow-up visits
Is a patient of the University of Texas Southwestern Medical Center physicians
None
Cancer patients, healthy volunteers
Case-only
Cross-sectional
biologic sample preservation procedure
Other interventionmedical chart review
Other interventionquestionnaire administration
Other interventionMaintenance a Tissue Resource and Registry/Database
Maintenance and creation of a University of Texas Southwestern Medical Center (UTSW) Radiation Oncology Tissue Resource and Registry/Database
Local recurrence
To document local recurrence by treatment regimen and disease site.
Distant metastasis
To document distant metastasis by treatment regimen and disease site.
Overall survival
To document overall survival by treatment regimen and disease site.
Toxicity by treatment regimen
To document toxicity by treatment regimen and disease site.
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