Review clinical trials related to Unspecified Adult Solid Tumor, Protocol Specific. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.
Patients with advanced solid tumors referred to the Phase 1 Unit are offered mapping of GA for identification of pts who could benefit from a personalized treatment.
Solid tumor [+5]
Life expectancy < 3 months [+3]
RATIONALE: Collecting and storing samples of tissue from patients with cancer to test in the laboratory may help the study of cancer in the future. PURPOSE: This research study is collecting tissue samples from patients with cancer undergoing radiation therapy. Healthy participants will also be allowed on the trial so their samples can be used in comparison to patients with malignancy
Pathologically-proven diagnosis of malignancy [+10]
RATIONALE: Gathering information about older patients with cancer may help the study of cancer in the future. PURPOSE: This research study is gathering information from older patients with cancer into a registry.
Patients must have an appointment at the North Carolina Cancer Hospital and agre... [+2]
RATIONALE: Collecting and storing samples of tissue or blood from patients with cancer for study in the laboratory may help the study of cancer in the future PURPOSE: This research study is collecting and storing blood and tissue samples from patients with suspected solid tumors.
Signed protocol specific informed consent prior to registration/randomization. [+1]
This research trial studies using genomic profiling to recommend anticancer treatment to patients with cancer that has spread beyond the original site of the tumor (metastatic cancer). Genomic profiling studies the deoxyribonucleic acid (DNA) of a tumor to detect genetic changes or abnormalities. This information can then be used to recommend treatments that may be more likely to result in a beneficial response. It is not yet known whether genomic profiling will detect abnormalities that can be used to make treatment recommendations and whether treatment based on genomic profiling is more effective than standard treatment.
Understand and provide written informed consent and Health Insurance Portability... [+6]
Have lesions that are not accessible to biopsy or not planned for biopsy as part... [+5]
A modular, first time in human, open label, multiple dose, accelerated escalation with cohort expansion study of the safety and pharmacokinetics of intravenous infusion of CP-506, a tumor agnostic Hypoxia Activated Prodrug in patients with HRD/FAD solid tumours or tumor types with high incidence of HRD/FAD in monotherapy or in combination with carboplatin or patients with solid tumour and oligoprogressive disease receiving immune checkpoint inhibitors (ICI): a phase I-IIa clinical trial
Male or female, aged 18 years or more at the time of signing the informed consen... [+14]
Prior radiotherapy to more than 25% of bone marrow [+30]