Compare Hemodynamic Effect of Oxytocin Bolus and Infusion During Cesarean Section Under Spinal Anesthesia

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-40
SponsorHayatabad Medical Complex

About this trial

Oxytocin is routinely used during a cesarean section to promote uterine contraction and prevent postpartum hemorrhage. It is typically administered immediately after delivery of the baby, either as a slow intravenous bolus followed by a continuous infusion or as an infusion alone, depending on clinical protocols. By stimulating the uterine muscles to contract, oxytocin helps reduce blood loss and facilitates uterine involution. Care is taken to avoid rapid high-dose administration, as this may lead to side effects such as hypotension and tachycardia

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

None

Disqualifiers

None

Trial design

Design model

Parallel

Treatments tested in this trial

  • Oxytocin bolus

    Drug

    5IU OXYTOCIN diluted in 5ml normal saline, given as bolus over 5 second

Treatment groups

262 Participants
are divided into 2 treatment groups
Group A: Oxytocin bolus groupExperimental treatment 1 intervention
Group B: Oxytocin infusion groupActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Heart rate and blood pressure changes in beats per minute and mmHg respectively by comparing intravenous bolus and infusion oxytocin during Cesarean section under spinal anesthesia

Comparison of iv bolus and infusion technique of oxytocin causing changes hemodynamic are noticed while it is given to patient undergoing Cesarean section under spinal anesthesia

Time frame
Over period of giving the drug and after 2 to 5 mins of giving drug

Secondary outcomes

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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This trial is not recruiting at the moment. You can still explore other options: