Comparing Tear Proteomics Profile in Dry Eye Disease pre-and Post-treatment With Low Level Light Therapy
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age21+
SponsorSingapore National Eye Centre
About this trial
The purpose of this research study is to understand the mechanism of action of low level light therapy and also potentially yield markers associated with good treatment response. Low-level light therapy is light-based treatment delivered through advance eye-light device. This therapy uses light energy to provide energy to the meibomian gland cells to slow down age-ing, improve tear stability and reduce inflammation.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Must be eligible for, and have consented for low level light therapy
Must not have presented to the clinic for an acute eye problem such as visual loss or painful eye
Ability to give informed consent.
Age more or equals to 21 years old.
Disqualifiers
Patients who are unable to or decline to give consent.
Age less than 21 years old.
Patients who presented to the clinic for an acute eye problem such as visual loss or painful eye.
Pregnant
Trial population
Patient undergoing low level light therapy that met the study inclusion and exclusion
Trial design
Design model
Other
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
30 Participants
are grouped into 1 trial groupGroup A: Patients undergoing low level light therapy
Trial outcomes
Primary outcomes
1
Comparing tear proteomics profile in dry eye disease pre-and post-treatment with low level light therapy
Aim 1: Tear proteomic profile of MGD patients with DED pre- and post-treatment with LLLT will be profiled Aim 2: Baseline tear cytokine levels will be measured using the novel Olink 500-plex technology in DED patients with MGD undergoing LLLT
Time frame
Baseline visit and Post Baseline visit 3 months (+3 weeks).Sponsors and contacts
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Source ClinicalTrials.gov