This study will evaluate the performance and acceptability of different sampling methods for measuring vitamin D, specifically 25-hydroxyvitamin D₂ and 25-hydroxyvitamin D₃.
Adults aged 18 years or older.
Current healthcare staff or staff volunteers.
Already consented to use the routine dried blood spot (DBS) vitamin D service.
Able and willing to provide all three sample types- routine DBS finger-prick sample, a Tasso+ upper-arm self-collected capillary sample, and a venous blood sample taken by a trained Trust phlebotomist.
Under 18 years of age
Not a member of staff or staff volunteer
Known difficulty with blood sampling, such as a history of fainting, severe needle phobia, or conditions that make venepuncture unsafe.
Skin conditions or injuries on the upper arm that would prevent safe use of the Tasso+ device.
Single group
Vit D Tasso+
DeviceBlood collected using Tasso device
Agreement between Tasso+ capillary serum and venous serum 25(OH)D
Continuous 25(OH)D₂ and 25(OH)D₃ concentrations (nmol/L)
User acceptability
Pain, on a scale from 1-5 1= no pain. 5= worse pain
User acceptability
Ease of Use: how easy or difficult each method was to complete 1= Very difficult, 5=Very easy Dried Bloodspot Venepuncture Tasso+
User acceptability
Clarity of Instructions: how clear were the instructions you were given? 1= Not clear at all, 5=Extremely clear Dried Bloodspot Venepuncture Tasso+
User acceptability
Safety: How safe did each method feel to you ? 1= Very unsafe, 5=Very safe Dried Bloodspot Venepuncture Tasso+
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This trial is not recruiting at the moment. You can still explore other options:
