Comparison Between Non-contrast Magnetic Resonance Angiography and Carotid Doppler in Cerebrovascular Stroke

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorSohag University

About this trial

This prospective observational study aims to compare the diagnostic performance of non-contrast magnetic resonance angiography (NC-MRA) and carotid Doppler ultrasonography in the evaluation of carotid artery disease among patients with ischemic cerebrovascular stroke or transient ischemic attack. A total of 200 adult patients presenting to Sohag University Hospital will undergo both imaging modalities. The study will assess the agreement between NC-MRA and carotid Doppler in detecting and grading carotid artery stenosis according to the NASCET criteria, with the goal of evaluating the clinical utility of each technique and optimizing imaging strategies for the assessment of cerebrovascular stroke.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adults aged 18 years or older.

Clinically diagnosed ischemic stroke or transient ischemic attack (TIA).

Imaging performed within 7-14 days of symptom onset.

Hemodynamically stable and suitable for magnetic resonance imaging (MRI).

Disqualifiers

Hemorrhagic stroke.

Previous carotid artery stenting.

Non-MRI-compatible pacemakers or other MRI-incompatible implants.

Cochlear implants.

Trial population

Adult patients (≥18 years) presenting to Sohag University Hospital with a clinical diagnosis of ischemic stroke or transient ischemic attack (TIA) who are eligible for magnetic resonance imaging and carotid Doppler ultrasonography.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

200 Participants
are grouped into 1 trial group
Group A: Patients with Ischemic Stroke or Transient Ischemic Attack

Trial outcomes

Primary outcomes

1

Internal Carotid Artery Stenosis Grade (according to NASCET criteria) assessed by Non-contrast Magnetic Resonance Angiography and Carotid Doppler ultrasonography.

Internal carotid artery stenosis grade in patients with ischemic stroke or transient ischemic attack determined according to the North American Symptomatic Carotid Endarterectomy Trial (NASCET) criteria using non-contrast magnetic resonance angiography and carotid Doppler ultrasonography. The stenosis grades obtained by the two imaging modalities will be compared.

Time frame
At the baseline imaging visit (within 7-14 days of symptom onset).

Secondary outcomes

Other outcomes

Sponsors and contacts

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