This study aims to evaluate the performance of the TetraGraph on two muscle groups: the adductor pollicis and the abductor digiti minimi. Theese muscles are located on the arms. Key time points for assessment will include the onset of neuromuscular blockade and the recovery from rocuronium blockade using sugammadex.
Age > or = 18 years old
Patients willing to participate and provide an informed consent
Patients undergoing elective surgical procedures that require use of NMBA agents (rocuronium) administered intraoperatively.
Patients with disorders, such as stroke, carpal tunnel syndrome, broken wrist with nerve damage, Dupuytren contracture, or any similar wrist injury.
Patients with systemic neuromuscular diseases such as myasthenia gravis.
Patients with significant organ dysfunction that can significantly affect pharmacokinetics of neuromuscular blocking and reversal agents, i.e., severe renal impairment or end-stage liver disease.
Patients having surgery that would involve prepping the arm into the sterile field.
Patients who receive a muscle relaxant (rocuronium bromide) for their operation to aid intubation and surgical exploration.
Case-only
Prospective
Not listed
The rate of recovery following sugammadex administration as recorded simultaneously from the hand (adductor pollicis) and fifth digit (abductor digiti minimi) muscles
the time in seconds between the administration of the suggamedex and TOF 100%.
The incidence of postoperative residual weakness
The secondary endpoint is the incidence of postoperative residual weakness at the time of extubation at a center that predominately utilizes quantitative monitoring (defined as TOFR \<0.90).
Click on the lead sponsor to view all of their trials.
Tamas Vegh, MD
Lead sponsor
University of Debrecen
Sponsor institution
