Postoperative Residual Curarization

3

Review clinical trials related to Postoperative Residual Curarization. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Postoperative Residual Neuromuscular Block and Passive Smoke Exposure in Pediatric Dental Patients

Postoperative residual neuromuscular block (PRNB) may persist despite apparent clinical recovery from neuromuscular blockade and may increase the risk of postoperative respiratory complications. Quantitative neuromuscular monitoring is therefore important for identifying incomplete neuromuscular recovery. This prospective, single-center observational cohort study aims to determine the incidence of PRNB in pediatric patients undergoing dental procedures under general anesthesia with rocuronium and to evaluate the association between passive smoke exposure and PRNB. Children aged 2-12 years will undergo quantitative neuromuscular assessment using the TOF-Watch SX after clinical extubation and admission to the post-anesthesia care unit (PACU). PRNB will be defined as a train-of-four (TOF) ratio \<0.9. The incidence of PRNB will be determined, and its association with passive smoke exposure and perioperative clinical variables will be evaluated.

Participants needed: 55
Trial details
Age: 2-12Biological sex: AllType: ObservationalSponsor: Istanbul University - CerrahpasaUpdated: Sep 21, 2026Locations: 1
Eligibility criteria

Children aged 2-12 years [+3]

Known neuromuscular disease [+4]

Status: Recruiting

Comparison of Adductor Pollicis and Abductor Digiti Minimi Muscles (Thumb Vs. Fifth Digit) As Sites for Neuromuscular Monitoring with Electromyography

This study aims to evaluate the performance of the TetraGraph on two muscle groups: the adductor pollicis and the abductor digiti minimi. Theese muscles are located on the arms. Key time points for assessment will include the onset of neuromuscular blockade and the recovery from rocuronium blockade using sugammadex.

Participants needed: 46
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Tamas Vegh, MDUpdated: Nov 15, 2024Locations: 2
Eligibility criteria

Age > or = 18 years old [+2]

Patients with disorders, such as stroke, carpal tunnel syndrome, broken wrist wi... [+5]

Status: Recruiting

Measuring Upper Airway Cross Sectional Areas During Residual Neuromuscular Blockade and After Reserval

In our study, the investigators sought to answer the question of how the retroglossal pharyngeal areas measured after extubation of patients compare to baseline (before muscle relaxation) values. The investigators also investigated how these areas change as a function of TOF ratios measured at extubation, thus looking for a correlation between residual muscle relaxant effect and airway area.

Participants needed: 20
Trial details
Age: 18-65Biological sex: AllType: ObservationalSponsor: Tamas Vegh, MDUpdated: Aug 12, 2024Locations: 1
Eligibility criteria

ASA 1-3; [+5]

drugs affecting neuromuscular function (magnesium, aminoglycosides); [+6]