Measuring Upper Airway Cross Sectional Areas During Residual Neuromuscular Blockade and After Reserval

ConditionsPostoperative Residual Curarization Airway Obstruction on Anaesthetic Emergence

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18-65

SponsorTamas Vegh, MD

About this trial

In our study, the investigators sought to answer the question of how the retroglossal pharyngeal areas measured after extubation of patients compare to baseline (before muscle relaxation) values. The investigators also investigated how these areas change as a function of TOF ratios measured at extubation, thus looking for a correlation between residual muscle relaxant effect and airway area.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

ASA 1-3;

BMI 18.5-25 (normal body weight);

men/women in equal proportion;

duration of surgeries at least ≥ 30 minutes;

Disqualifiers

drugs affecting neuromuscular function (magnesium, aminoglycosides);

difficult airway, expected difficult intubation;

pregnancy (pregnancy test for women of childbearing age to rule out pregnancy we finish);

breastfeeding;

Trial population

Patients who receive a muscle relaxant (rocuronium bromide) for their operation to aid intubation and surgical exploration.

Trial design

Design model

Case-only

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

The differences in retroglossal pharyngeal cross sectional areas (inspiration and exspiration) measured at different TOF values

The differences in retroglossal pharyngeal cross sectional areas (inspiration and exspiration) measured at different train of four TOF values, and changes in these values compared to (initial) retroglossae pharyngeal areas detected before administration of muscle relaxants. Areas are measured in pixels and the rate of reduction of areas is expressed as a percentage.

Time frame

before intubation, after extubation of the trachea

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Tamas Vegh, MD

Lead sponsor

University of Debrecen

Sponsor institution

Source ClinicalTrials.gov

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