Comparison of FCV and VCV in One-Lung Ventilation

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorDr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

About this trial

One-lung ventilation (OLV) is commonly used during thoracic surgery but may negatively affect lung mechanics and gas exchange. Different ventilation strategies are used during OLV, and their effects on respiratory parameters remain an important clinical concern.

Flow-controlled ventilation (FCV) is a newer ventilation mode that allows precise control of inspiratory and expiratory flow, potentially improving lung mechanics and gas exchange. Volume-controlled ventilation (VCV) is a widely used conventional ventilation strategy during thoracic anesthesia.

The FCVOLVent study is a multicenter, prospective observational study designed to compare the effects of FCV and VCV during one-lung ventilation in adult patients undergoing thoracic surgery. Patients will be ventilated with either FCV or VCV as part of routine clinical practice.

The study aims to evaluate respiratory mechanics and oxygenation parameters, including the PaO₂/FiO₂ ratio, airway pressures, lung compliance, and mechanical power during surgery. Data will be collected at predefined time points during one-lung ventilation.

The results of this study are expected to provide real-world clinical evidence on the potential advantages and limitations of flow-controlled ventilation compared with volume-controlled ventilation during one-lung ventilation.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

None

Trial population

Adult patients aged 18 years and older undergoing thoracic surgery requiring one-lung ventilation with flow-controlled ventilation (FCV) or volume-controlled ventilation (VCV).

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

60 Participants
are grouped into 2 trial groups
Group A: All participants
Group B: Prospective observational cohort study

Trial outcomes

Primary outcomes

1

Oxygenation Capacity

PaO₂/FiO₂ Ratio

Time frame
Intraoperative period (during one-lung ventilation)

Secondary outcomes

1

Respiratory parameters

mechanical power (MP)

Time frame
Intraoperative period (during one-lung ventilation)

Other outcomes

Sponsors and contacts

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Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

Lead sponsor

Kocaeli City Hospital

Collaborator

Yedikule Training and Research Hospital

Collaborator

Sakarya University

Collaborator

Ataturk University

Collaborator