Comparison of Paravertebral Versus Epidural Block for Post-thoracotomy Pain Control

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorHospital de Clinicas de Porto Alegre

About this trial

This is a randomized, assessor-blinded, non-inferiority clinical trial comparing continuous thoracic paravertebral block (BPV) versus continuous thoracic epidural block (BPD) for postoperative pain control in adult patients undergoing elective open thoracotomy with one-lung ventilation. The primary outcome is the mean pain intensity at rest assessed by the Numeric Verbal Scale (NVS 0-10) during the first 48 hours after surgery. A total of 80 participants will be randomized 1:1 at Hospital de Clínicas de Porto Alegre, Brazil. The study aims to determine whether BPV provides non-inferior analgesia compared to BPD, with a potential advantage of less hemodynamic interference and better postoperative mobilization.

Eligibility criteria

Qualifiers

Patients aged 18 years or older;

Elective thoracic surgeries requiring open thoracotomy;

American Society of Anesthesiologists (ASA) physical status I to III.

Disqualifiers

Pregnancy or lactation;

Urgent or emergency surgeries;

Contraindications to epidural catheter insertion or neuraxial anesthesia;

Infection at the proposed block site;

Trial design

Treatments tested in this trial

  • Continuous Thoracic Paravertebral Block
  • Continuous Thoracic Epidural Block

Treatment groups

80 Participants
are divided into 2 treatment groups