About this trial
The aim of our study was to compare the effects of interscalene block alone and the combination of interscalene block and superficial cervical block on cerebral oxygenation, carotid artery diameter, intraoperative hemodynamics, laboratory parameters, clinical course and postoperative pain in patients undergoing shoulder surgery.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
18-65 years patient
American Society of Anesthesiologists (ASA) I-II patient
Disqualifiers
Age < 18 years or > 65 years
History of carotid endarterectomy
History of cerebrovascular accident(CVA)
Body Mass index (BMI)>35 kg/m²
Trial design
Parallel
Treatments tested in this trial
Interscalene brachial plexus block
Procedure/SurgeryAfter sedating the patient with 2 mg midazolam, baseline values will be obtained, and an interscalene block will be performed under ultrasound guidance. Before the block, rSO2 values of both hemispheres of the brain and carotid artery diameter (at T1 and T5 times) will be measured and recorded using a NIRS probe at T2: 5 minute(min), T3: 10 min, T4: 15 min, and T5: 20 min. To assess the quality of the block, the sensory block will be evaluated at 20 minutes. The patient will be placed in a supine position, and after the first rSO2 value is obtained at T6, rSO2 values will be recorded at T7: 10 min, T8: 30 min, T9: 60 min, T10: surgical completion, and T11: 5 min postoperatively in the supine position. Bilateral carotid diameter(mm) will be measured at T6, T10, and T11. Before any postoperative analgesia is administered, the time of the patient's first pain and their need for analgesic will be recorded.
Interscalene brachial plexus block and superficial cervical plexus block
Procedure/SurgeryAfter sedating the patient with 2 mg midazolam, baseline values will be obtained, and a combined interscalene and superficial cervical block will be performed under ultrasound guidance. Before the block, rSO2 values of both hemispheres of the brain and carotid artery diameter(mm) (at T1 and T5 times) will be measured and recorded using a NIRS probe at T2: 5 minute, T3: 10 minute, T4: 15 minute, and T5: 20 minute. To assess the quality of the block, the sensory block will be evaluated at 20 minutes. The patient will be placed in a supine position, and after the first rSO2 value is obtained at T6, rSO2 values will be recorded at T7: 10 minute, T8: 30 minute, T9: 60 minute, T10: surgical completion, and T11: 5 minute postoperatively in the supine position. Bilateral carotid diameter(mm) will be measured at T6, T10, and T11. Before any postoperative analgesia is administered, the time of the patient's first pain, and their need for analgesic will be recorded.
Treatment groups
Trial outcomes
Primary outcomes
The effect of regional anesthesia on cerebral oxygenation
We plan to investigate the effect of interscalene block or a combination of interscalene and superficial cervical block on oxygenation of both hemispheres of the brain using a NIRS probe.
Secondary outcomes
The effect of regional anesthesia on carotid artery diameter
The diameter of the common carotid artery will be measured longitudinally in millimeters(mm) with the transverse probe of the ultrasound at specified times.
The effect of the two-block method on the duration of first postoperative analgesia requirement and opioid consumption
The patient will not receive routine analgesia postoperatively. The time(hour) of the first request for analgesia and the amount of opioid consumption within the first 24 postoperative hours will be evaluated.
Other outcomes
Effect of block type on saturation
Peripheral oxygen saturation will be measured noninvasively from the finger using pulse oximetry.
Effect of block type on blood pressure
Blood pressure will be measured noninvasively from the arm
Effect of block type on heart rate
Heart rate will be measured continuously using electrocardiography
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