About this trial
Propofol and Isoflurane are commonly used sedative agents in general anaesthesia.Both these drugs have a side effect of decreasing blood pressure which when used optimally can be used to acheive controlled hypotention. So, it provides a better visiblity of surgical filed to the surgeons.This RCT compares propofol infusion vs isoflurane inhalation for inducing controlled hypotension during endoscopic sinus surgery. The goal is to assess which agent better controls blood pressure, improves surgical field visibility, and impacts recovery. It likely measures outcomes like hemodynamics, bleeding, and surgeon satisfaction.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Either male/female Age 18-65 Patients undergoing endoscopic sinus surgery as per the operational definition
Disqualifiers
Patients with cardiovascular disease Patients with pregnancy Patients with coagulopathy Patients on beta blockers or calcium channel blockers
Trial design
Parallel
Treatments tested in this trial
Propofol
DrugIntravenous propofol infusion (starting dose 12mg/kg/hr and titrated accordingly) given to patients as sedative undergoing endscopic sinus surgery for hemodynamic stability
Isoflurane
DrugIsoflurane inhalation (1-2% end tidal) used in patients as sedative undergoing endoscopic sinus surgery for hemodynamic stability
Treatment groups
Trial outcomes
Primary outcomes
Surgical field visibility
Surgical field visibility
Sponsors and contacts
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This trial is not recruiting at the moment. You can still explore other options: