"Constitution of a Biological Collection to Establish Preclinical Translational Models for the Study of Tumors and Chronic Liver Diseases".

ConditionsChronic Liver Disease and Cirrhosis Liver Cancer Non-Alcoholic Fatty Liver Disease Non-Alcoholic Steatohepatitis Viral Hepatitis B Viral Hepatitis C Viral Hepatitis D

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18+

SponsorInstitut National de la Santé Et de la Recherche Médicale, France

About this trial

Development of preclinical translational models for chronic liver tumors and diseases study, such as spheroids cultured in autologous medium and murine xenograft models to test the efficacy of new therapeutic strategies.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients

diagnosed with chronic liver disease (viral or not)

diagnosed with at least one liver nodule for which a biopsy is planned as part of the care

for hepatobiliary surgery planned as part of care

Disqualifiers

Minor patients

Patients under legal protection,

Patients subject to legal protection or unable to express their consent,

Patients in a situation of social fragility,

Trial population

Population with hepato-bilio-pancratic disease (tumor, viral infection, injury)

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Blood sample during surgery
Procedure/Surgery
During the hepato-bilio-pancreatic surgery, blood is drawn.
Taking an additional biopsy
Procedure/Surgery
As part of the treatment, an additional biopsy is executed and blood is drawn.
Blood sample during diagnostic test
Diagnostic test
Blood sample as part of the care

Treatment groups

800 Participants

are divided into 3 treatment groups

Group A: Hepato-bilio-pancreatic surgery1 intervention

Group B: biopsy of the hepatic parenchyma1 intervention

Group C: Viral chronic infection1 intervention

Trial outcomes

Primary outcomes

Surgery for a hepato-bilio-pancreatic issue

Patients whom hepato-bilio-pancreatic disease

Time frame

through study completion, an average of 8 year

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Institut National de la Santé Et de la Recherche Médicale, France

Lead sponsor

Source ClinicalTrials.gov

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