Continuous Interscalene Blocks and Rebound Pain

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Calgary

About this trial

The primary objectives of this present study are to examine whether a continuous interscalene block of a total duration of 48 hours reduces the incidence of rebound pain comparatively to single-shot interscalene block, through the evaluation of the NRS scores at rest and on movement in the postoperative period at 24, 48, 72 and 96 hours as well as the total opioid consumption in the same timeframe for patients undergoing total shoulder arthroplasty.

Rebound pain has been defined in some studies as the "the transition from well-controlled pain (numerical rating scale \[NRS\] ≤3) while the block is working to severe pain (NRS ≥7) within 24 h of block performance."

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adults aged >18 years of age

ASA I-III

Scheduled for elective ambulatory total shoulder arthroplasty.

Disqualifiers

ASA IV

Revision surgery

Contraindication to regional anesthesia (such as allergy to local anesthetics, systemic anticoagulation, local infection)

Preoperative chronic pain or opioid use

Trial design

Design model

Parallel

Treatments tested in this trial

  • Continuous interscalene nerve block

    Drug

    This Interventional Group will receive a continuous interscalene block via a catheter for a duration of 48 hours with ropivacaine 0.2% at a fixed 5 mL/hour rate.

  • Interscalene Block

    Drug

    This control group will receive a single shot interscalene block with 20 mL of ropivicaine 0.2%.

Treatment groups

154 Participants
are divided into 2 treatment groups
Group A: Single Shot Interscalene BlockActive comparator 1 intervention
Group B: Continuous Interscalene BlockExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

incidence of Rebound pain within 96 hours postoperatively

The incidence of Rebound Pain, defined as an NRS score of \< 3 during an effective block to an NRS \> 7 within 24 hours of block resolution. This will be analyzed as a binary variable (yes/no)

Time frame
This outcome will be measured within 24 hours of block resolution, for up to 96 hours after the initial block realization.

Secondary outcomes

Other outcomes

Sponsors and contacts

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