Total Shoulder Arthroplasty

2

Review clinical trials related to Total Shoulder Arthroplasty. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Continuous Interscalene Blocks and Rebound Pain

The primary objectives of this present study are to examine whether a continuous interscalene block of a total duration of 48 hours reduces the incidence of rebound pain comparatively to single-shot interscalene block, through the evaluation of the NRS scores at rest and on movement in the postoperative period at 24, 48, 72 and 96 hours as well as the total opioid consumption in the same timeframe for patients undergoing total shoulder arthroplasty. Rebound pain has been defined in some studies as the "the transition from well-controlled pain (numerical rating scale \[NRS\] ≤3) while the block is working to severe pain (NRS ≥7) within 24 h of block performance."

Participants needed: 154
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of CalgaryUpdated: Aug 19, 2026Locations: 1
Eligibility criteria

Adults aged >18 years of age [+2]

ASA IV [+6]

Status: Recruiting

Addition of a Pectoserratus Block to Interscalene Block in Patients Undergoing Total Shoulder Replacement

The use of ISB in patients undergoing total shoulder arthroplasty (TSA) is the gold standard and results in significantly reduced pain scores and opioid use. However, patients still have pain and the majority require opioids postoperatively as the interscalene block (ISB) doesn't cover all of the dermatomes impacted during TSA. A pectoserratus block typically provides coverage to additional dermatomes that are impacted during TSA. Currently ISB is performed for every patient and perform a pectoserratus block to a portion of our patients undergoing TSA. The purpose of the study is to determine if the addition of the pectoserratus block to the ISB will results in improvement in pain control and decrease in opioid use, among patients undergoing TSA. This is a randomized prospective controlled trial. All patients undergoing total shoulder arthroplasty or reverse total shoulder arthroplasty aged 18-85 will be considered eligible for the study. Participants will be randomized to one of 2 treatment groups. Group 1 will receive an ultrasound guided pectoserratus block with 25 mL of 0.25% bupivacaine. Group 2 will be the control and receive an ultrasound guided pectoserratus block with 25 mL of saline. The drug will be administered by the anesthesiologist in-charge of the participant's care or an anesthesiologist who is a part of the study team.

Participants needed: 110
Trial details
Phase: Phase 4Age: 18-85Biological sex: AllType: InterventionalSponsor: University of MinnesotaUpdated: Mar 17, 2026Locations: 1
Eligibility criteria

Patients undergoing total shoulder arthroplasty or reverse total shoulder arthro... [+1]

Patients who have an exclusion to regional anesthesia such as pre-existing nerve... [+4]