Correlation of Dermoscopic Findings With Histopathological Features and Invasion Depth in Cutaneous Squamous Cell Carcinoma

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorIstanbul Training and Research Hospital

About this trial

This is a retrospective study including patients diagnosed with cutaneous squamous cell carcinoma between 2016 and 2025. Demographic, clinical, histopathological, and dermoscopic data were obtained from hospital records. Dermoscopic images taken with the FotoFinder dermoscope were independently evaluated by two dermatologists in a blinded manner. In addition, images were labeled using computer software and analyzed to measure the proportion of specific dermoscopic structures within the total lesion area. These quantitative data were used to examine the relationship between dermoscopic features and histopathological findings.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

None

Trial population

The study population consists of adult patients aged 18 to 100 years who were diagnosed with cutaneous squamous cell carcinoma and treated with total surgical excision between 2016 and 2025. Only cases with complete clinical, dermoscopic, and histopathological records, including documented tumor differentiation and invasion depth, were included. No additional diagnostic or therapeutic procedures were performed as part of the study.

Trial design

Design model

Case-only

Time perspective

Retrospective

Treatments tested in this trial

Not listed

Trial groups

238 Participants
are grouped into 1 trial group
Group A: Cutaneous Squamous Cell Carcinoma Patients

Trial outcomes

Primary outcomes

1

Correlation between dermoscopic features and tumor invasion depth

The association between predefined dermoscopic features and histopathological tumor invasion depth will be evaluated using quantitative and qualitative dermoscopic assessments.

Time frame
Retrospective analysis of records from 2016 to 2025

Secondary outcomes

Other outcomes

Sponsors and contacts

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