About this trial
Exercise retraining improves the prognosis and quality of life of patients with chronic lung or circulatory diseases. However, exercise intolerance may be caused by excessive ventilatory. Exposure to oxygen-replete air reduces this ventilatory overload, improves sleep and enhances responses to exercise. This study examine the impact of the acute manipulation of oxygen availability during inter-exercise recovery period of an intermittent cycling exercise on perceptual responses.
this randomized, controlled, study include adult patient with COPD. On separate days, 50 patients with COPD completed four sets of 4-min at 85% of VO2peak intercept by 3-min of passive recovery in two randomized between-sets recovery conditions. Rating exertion perception, gaz exchanges, heart rate, sleep quality and nocturnal heart rate variability were assessed.
Hypoxic exposure during inter-repetition recovery phases would reduce the ventilatory load during exercise. What's more, patients would not be forced to perform the sporting gesture in a restricted space or wearing a mask, limiting dyspnea and the perceived difficulty of the effort. Lastly, the induction of hypoxic stress during the re-training session helped to improve patients' sleep.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
from 40 to 60 years
follow-up in the pneumology unit of CHU Amiens - Picardie
Chronic Obstructive Pulmonary Disease stade II
Body mass index from 20 to 30 kg.m-2
Disqualifiers
None
Trial design
Parallel
Treatments tested in this trial
Normobaric hypoxia
Other interventionNormobaric hypoxia (inspired oxygen fraction of 12.9%) applied between-sets recovery periods
normoxic condition
Other interventionBetween-sets recovery periods under normoxic condition
Treatment groups
Trial outcomes
Primary outcomes
Perception Exertion score with CR10
The modified Borg CR10 RPE scale measures exertion on a scale of 0 (no exertion or resting) to 10 (pushing yourself to the max).
Secondary outcomes
Cardiorespiratory responses to exercise
Cardiorespiratory responses to exercise is measured with gaseous exchange volumes
Sponsors and contacts
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