Creatine Supplementation in Young Healthy Adults
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-39
SponsorUniversity of Regina
About this trial
The purpose is to compare the effects of bolus ingestion (5 grams) vs. intermittent ingestion (2 x 2.5 grams) of creatine supplementation vs. placebo for 21 days on measures of body composition (lean tissue mass-indicator of muscle mass, total body water) and muscle performance (i.e., power, strength, endurance).
Eligibility criteria
This trial accepts healthy volunteersQualifiers
if you are 18-39 years of age
if you have not been performing resistance training for at least 4 weeks prior to the start of the study.
Disqualifiers
if you are pregnant or nursing
have taken creatine monohydrate within 30 days prior to the start of the study
if you have pre-existing allergies to the placebo (corn-starch maltodextrin)
Trial design
Design model
Parallel
Treatments tested in this trial
Creatine
Dietary supplementCreatine monohydrate
Placebo
Dietary supplementMaltodextrin
Treatment groups
42 Participants
are divided into 3 treatment groupsGroup A: Creatine BolusExperimental treatment 1 intervention
Group B: Creatine IntermittentExperimental treatment 1 intervention
Group C: PlaceboPlacebo comparator 1 intervention
Trial outcomes
Primary outcomes
1
Whole-body lean mass (kg)
Bioelectrical impedance analysis
Time frame
baseline, day 212
Strength
1-repetition maximum leg press and chest press (kg)
Time frame
baseline, day 213
Endurance
Repetitions to fatigue for leg press and chest press (total number)
Time frame
baseline, day 214
Hydration
Total body water (kg) using bioelectrical impedance analysis
Time frame
baseline, day 21Sponsors and contacts
Click on the lead sponsor to view all of their trials.
University of Regina
Lead sponsor
Iovate Health Sciences International Inc
Collaborator
Source ClinicalTrials.gov