Health TrialsbyHealthPanel

Deep Caries in Mature Teeth With Reversible Pulpitis

ConditionDeep Caries
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-40
SponsorMinia University

About this trial

This clinical trial will be conducted to clinical, radiographical and histological evaluation of pulp condition with reversible pulpities after total and selective removal of primary and secondary caries (randomized clinical trial and exo-vivo study)

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

The patient's age from 18 years to 40 years old

Non -contributory medical history (ASA1)

Mature permanent posterior teeth with primary or secondary deep caries extending ≥ 2/3 of dentin

The tooth should give a positive response to cold testing

Disqualifiers

Systemic medical conditions, pregnancy, alcoholic and smoker patients. 2- Teeth with spontaneous pain or percussion sensitivity in periodontal lesions, external or internal root resorption, sinus opening, mobility, or abscessed tooth. 3- Radiographic evidence of widened periodontal space, broken or interrupted lamina dura, and periapical radiolucency. 4- Intensified erosion damage or periodontitis. Patient reported clenching or bruxism, hopeless or non-restorable teeth. Immature teeth. 5- Patients with physical disabilities preventing tooth brushing. Patient had removable partial denture abutments, dental abscesses, pulp lesions, atypical facial pain, or pulpitis. 6- Patients had non-carious lesions like abrasion, erosion, attrition, or abfraction.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Total caries removal

    Procedure/Surgery

    Total caries removal and application of bioactive material

  • Partial caries removal

    Procedure/Surgery

    Partial caries removal then application of biodentin

Treatment groups

144 Participants
are divided into 4 treatment groups
Group A: Total caries removal in primary cariesActive comparator 1 intervention
Group B: Total caries removal of secondary cariesActive comparator 1 intervention
Group C: Partial caries removal of primary cariesActive comparator 1 intervention
Group D: Partial caries removal of secondary cariesActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

clinical evaluation ………. Radiographic evaluation:

clinical evaluation: absence of pain , pulp vitality, ………. Radiographic evaluation: absence of any periapical lesion or recurrent caries

Time frame
1year

Secondary outcomes

1

histological evaluation and follow up

histological evaluation after one year. T (Time): follow up evaluation periods of pulp condition immediately post operative (base line ), after 3, 6, 9 and 12 month and exo-vivo study.

Time frame
1 year

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Minia University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: