Health TrialsbyHealthPanel

Development of a Transdiagnostic Intervention for Adolescents at Risk for Serious Mental Illness

ConditionsAnxiety DisordersPsychotic DisordersDepressive DisorderPsychosocial Functioning
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age14-19
SponsorMassachusetts General Hospital

About this trial

This research study aims to develop a brief group-based treatment called Resilience Training for Teens, then to test how well it protects high school students with mild symptoms of depression, anxiety, or having unusual feelings from developing mental illnesses.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Currently enrolled in 9th through 12th grade and between the ages of 14 and 19

Endorsed at least one psychotic experience

Provided contact information

Have a parent or legal guardian who is able and willing to provide written informed consent (if under the age of 18)

Disqualifiers

Currently prescribed psychotropic medication (not including medications for attention deficit/hyperactivity disorder), regardless of adherence

Currently obtaining psychotherapeutic intervention

Trial design

Design model

Parallel

Treatments tested in this trial

  • Resilience Training for Teens

    Behavioral

    A brief 6-session group-based behavioral intervention for high school aged teenagers at risk of a mental illness.

Treatment groups

70 Participants
are divided into 2 treatment groups
Group A: Resilience Training for TeensExperimental treatment 1 intervention
Group B: WaitlistNo intervention 0 interventions

Trial outcomes

Primary outcomes

1

Structured Interview of Psychosis-risk Syndromes (SIPS)

Subclinical psychotic symptoms that represent a risk of transdiagnostic mental illnesses. This semi-structured interview rates psychotic experiences, general symptoms, and functioning. The SIPS interview assesses positive, negative, disorganized, and general symptoms. The range of the Scale of Psychosis-risk Symptoms (SOPS) is 0-6, with a higher score representing more severe symptoms.

Time frame
1 year

Secondary outcomes

1

Child Behavior Checklist (CBCL)

Mental health symptoms in the teen rated by both the teen and the parent/guardian consisting of 113 items. The CBCL rates multiple domains across functioning and psychiatric diagnoses. It is scored on a 3-point Likert scale, with higher scores representing more severe symptoms.

Time frame
1 year
2

Global Functioning Social and Role Scales

Social and school/work functioning captured on this scale rated on a 10 point likert scale assessing functional and social functioning separately. Higher ratings represent richer functioning.

Time frame
1 year

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Massachusetts General Hospital

Lead sponsor

National Institute of Mental Health (NIMH)

Collaborator

Source ClinicalTrials.gov
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