Diaphragm Dysfunction and Ultrasound Perioperatively

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-100
SponsorKarolinska University Hospital

About this trial

This study aims at determining whether diaphragm ultrasound examining diaphragm thickening fraction, excursion and density before and after surgery can predict respiratory complications in the postoperative period.

Patients scheduled for major elective abdominal, pelvic or vascular surgery will be included in the study and diaphragm ultrasound is performed before surgery and after surgery in the postoperative ward. Physiological parameters, laboratory parameters, data on surgery and anesthesia and comorbidities will be registered. Complications such as pneumonia, desaturation, need for intubation and other respiratory events up to 30 days will be registered and later correlated with the diaphragm measurements.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

None

Disqualifiers

<18 years

Underlying chronic respiratory disease

Patients not able to give informed consent

Trial population

Adults undergoing elective (study 1) or acute (study 2) abdominal, pelvic or vascular surgery

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Diaphragm ultrasound

    Diagnostic test

    Diaphragm ultrasound will be used pre- and postoperatively. Diaphragm dysfunction will be diagnosed using the measurements diaphragm thickening fraction, diaphragm excursion and diaphragm density.

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

1

Pneumonia

Time frame
30 days
2

Respiratory insufficiency

Need for non-invasive or invasive ventilation

Time frame
30 days
3

Desaturation

Need for supplemental oxygen

Time frame
30 days

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Karolinska University Hospital

Lead sponsor

Karolinska Institutet

Collaborator