Diffusion MRI for Quantitative Assessment of Myofascial Pain

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-65
SponsorWeill Medical College of Cornell University

About this trial

The purpose of this study is to assess the diagnostic accuracy of diffusion MRI for evaluation of the jaw muscles for patients with masticatory myofascial pain syndrome.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Men and women 18-65 years of age

Ability to give informed consent

Symptoms meeting criteria for normal or latent/active temporomandibular myofascial pain

Disqualifiers

Contraindications to MRI scanning including severe obesity or difficulty in laying in a supine position, intracranial clips, metal implants, external metallic devices/objects/clips within 10mm of the head, suspected or confirmed metal in the eyes (history of welding or similar activity), claustrophobia, cardiac pacemaker or pacing wires

Pregnancy or breast feeding

Traumatic injury of masticatory muscles or temporomandibular joint within last 12 months

Mandibular fracture within last 12 months

Trial population

Participants from the community

Trial design

Design model

Case-control

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

90 Participants
are grouped into 2 trial groups
Group A: Normal
Group B: Latent/Active Pain Stage

Trial outcomes

Primary outcomes

1

Difference in mean diffusion MRI parameters of temporalis and masseter muscles between patients at the normal stage and those at the latent/active pain stage.

Time frame
Day 1

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Weill Medical College of Cornell University

Lead sponsor

National Center for Complementary and Integrative Health (NCCIH)

Collaborator

New York University

Collaborator