Masticatory Myofascial Pain Syndrome

2

Review clinical trials related to Masticatory Myofascial Pain Syndrome. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Does Addition of Medial Pterygoid Muscle Injection Improve the Outcome of Botulinum Toxin Therapy for Masticatory Myofascial Pain Syndrome?

Masticatory myofascial pain syndrome (MMPS) is a common and debilitating orofacial pain condition characterized by localized or referred pain originating from trigger points in the masticatory muscles. The condition significantly impairs quality of life, affecting mastication, speech, and psychosocial well-being. The masseter and temporalis muscles are the most frequently targeted muscles in conventional botulinum toxin type A (BoNT-A) therapy for MMPS; however, the medial pterygoid muscle, a primary jaw-closing muscle, is often overlooked due to its deep anatomical location and the technical challenges associated with its injection.

Participants needed: 111
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Fayoum UniversityUpdated: Aug 19, 2026Locations: 1
Eligibility criteria

Diagnosis of myogenous TMD/myalgia according to DC/TMD. [+6]

Predominantly arthrogenous TMD. [+10]

Status: Recruiting

Diffusion MRI for Quantitative Assessment of Myofascial Pain

The purpose of this study is to assess the diagnostic accuracy of diffusion MRI for evaluation of the jaw muscles for patients with masticatory myofascial pain syndrome.

Participants needed: 90
Trial details
Age: 18-65Biological sex: AllType: ObservationalSponsor: Weill Medical College of Cornell UniversityUpdated: Oct 1, 2025Locations: 2
Eligibility criteria

Men and women 18-65 years of age [+2]

Contraindications to MRI scanning including severe obesity or difficulty in layi... [+5]